Polymorphisms in Multidrug Resistance 1, Cyclooxygenase-2 and Breast Cancer Resistance Protein Genes and Risk of Colorectal Cancer, a prospective population based case control study. Running title: MDR1, COX-2, BCRP, NSAID, and Colorectal Cancer
نویسندگان
چکیده
Medical Department, and Clinical Biochemical Department, Viborg Regional Hospital, DK-8800 Viborg, Danish Cancer Society, Institute of Cancer Epidemiology, DK-2100 Copenhagen Department of Clinical Epidemiology, Aarhus University Hospital, DK-9100 Aalborg National Research Centre for the Working Environment, DK-2100 Copenhagen, National Food Institute, Technical University of Denmark, DK-2860 Søborg
منابع مشابه
Author's response to reviews Title: Polymorphisms in the xenobiotic transporter Multidrug Resistance 1 (MDR1) gene and interaction with meat intake in relation to risk of colorectal cancer in a Danish prospective case-cohort study. Authors:
Background: Genetic variation that modifies the gut barrier function or the inflammatory response may modify the risk of colorectal cancer (CRC). The intestinal xenobiotic transporters, Multidrug Resistance 1 (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) contribute to the intestinal homeostasis by exporting a broad spectrum of substrates including potential carcinogens from the...
متن کاملPolymorphisms in the xenobiotic transporter Multidrug Resistance 1 (MDR1) gene and interaction with meat intake in relation to risk of colorectal cancer in a Danish prospective case-cohort study
Background: Genetic variation that modifies the gut barrier function or the inflammatory response may modify the risk of colorectal cancer (CRC). The intestinal xenobiotic transporters, Multidrug Resistance 1 (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) contribute to the intestinal homeostasis by exporting a broad spectrum of substrates including potential carcinogens from the...
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